The manifestations of video game-related seizures (VGRS) in 10 patients aged 1-22 years examined and 25 case-reports reviewed are reported from the University of Washington School of Medicine, Seattle, WA. Prior susceptibility to epilepsy was evident in 8 patients with infrequent nonfebrile seizures, 4 with febrile seizures, and 2 with a positive family history, a total of 14 (40%). VGRS patterns were generalized tonic-clonic in 22 (63%), simple partial in 6 (19%), complex partial in 4 (11%), and absence in 2 (6%). Electroencephalographic epileptic patterns occurred in 11 of 21 patients (52%) and photoparoxysmal responses in 17 of 32 ((53%). Treatment was successful in 11 of 15 (73%) who only abstained from video game playing, in 3 of 6 who continued playing VGs and received anticonvulsant drugs, and 7 of 12 who abstained from VGs and also received AEDs. 
COMMENT. Abstinence from playing or watching video games is the treatment of choice for patients with VGR seizures. Anticonvulsant medication may be warranted in patients who also have unprovoked seizures. The authors suggest that VGRS are more frequent than commonly recognized.