Birth Asphyxia, Cerebral Metabolism and Head Size

J Millichap

doi:10.15844/pedneurbriefs-6-6-2

Author:

J Gordon Millichap

Northwestern University Feinberg School of Medicine, US

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Abstract

How to Cite: Millichap, J.G., 1992. Birth Asphyxia, Cerebral Metabolism and Head Size. Pediatric Neurology Briefs, 6(6), pp.42–42. DOI: http://doi.org/10.15844/pedneurbriefs-6-6-2

Studies of cerebral oxidative metabolism were carried out by phosphorus magnetic resonance spectroscopy during the first week of life in 52 infants with birth asphyxia admitted to the Neonatal Unit at University College Hospital, London. Cerebral phosphocreatine/inorganic phosphate concentration ratio was used as an index of oxidative metabolism and correlated with neurodevelopmental outcome and head growth at 1 year. [1]

COMMENT. The use of these neuroimaging and biochemical techniques should help in the prediction of outcome following neonatal encephalopathy. However, the complexity of the techniques may detract from their value in practice. [2]

Central diabetes insipidus as an unusual complication of hypoxic brain damage is described in 2 children at the Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan [3]. Both patients developed cardiopulmonary arrest after choking and both had hypernatremia and low urinary antidiuretic hormone concentrations in the terminal stages. The most common causes of central diabetes insipidus are tumors or trauma in the neurohypophyseal area.

References

Roth, SC Edwards, AD Cady, EB Delpy, DT Wyatt, JS Azzopardi, D et al. (1992). Relation between cerebral oxidative metabolism following birth asphyxia, and neurodevelopmental outcome and brain growth at one year. Dev Med Child Neurol Apr 199234(4): 285–295, DOI: https://doi.org/10.1111/j.1469-8749.1992.tb11432.x [PubMed]

Bax, M (1992). Birth asphyxia. Dev Med Child Neurol Apr 199234(4): 283–284, Editorial.DOI: https://doi.org/10.1111/j.1469-8749.1992.tb11431.x [PubMed]

Arisaka, O Arisaka, M Ikebe, A Niijima, A Shimura, N Hosaka, A et al. (1992). Central diabetes insipidus in hypoxic brain damage. Child’s Nerv Syst Mar 19928(2): 81–82, DOI: https://doi.org/10.1007/BF00298445 [PubMed]

[CIT0001] Roth, SC Edwards, AD Cady, EB Delpy, DT Wyatt, JS Azzopardi, D et al. (1992). Relation between cerebral oxidative metabolism following birth asphyxia, and neurodevelopmental outcome and brain growth at one year. Dev Med Child Neurol Apr 199234(4): 285–295, DOI: https://doi.org/10.1111/j.1469-8749.1992.tb11432.x [PubMed]

[CIT0002] Bax, M (1992). Birth asphyxia. Dev Med Child Neurol Apr 199234(4): 283–284, Editorial.DOI: https://doi.org/10.1111/j.1469-8749.1992.tb11431.x [PubMed]

[CIT0003] Arisaka, O Arisaka, M Ikebe, A Niijima, A Shimura, N Hosaka, A et al. (1992). Central diabetes insipidus in hypoxic brain damage. Child’s Nerv Syst Mar 19928(2): 81–82, DOI: https://doi.org/10.1007/BF00298445 [PubMed]

Reading: Birth Asphyxia, Cerebral Metabolism and Head Size

Neonatal Disorders

Birth Asphyxia, Cerebral Metabolism and Head Size

Author:

J Gordon Millichap

Northwestern University Feinberg School of Medicine, US

X close

Abstract

References