Concerns about potential effects on offspring have prompted a gradual change in antiepileptic drug usage in girls of child-bearing age in the last decade, according to a study at the School of Pharmacy and Institute of Child Health, University of London, UK. More females aged 12-18 years are prescribed lamotrigine (LTG) than carbamazepine or sodium valproate, and the 10-fold increase in LTG in females is significantly greater than the 5-fold rise for males. [1]
