Four young children who presented with acute thalamic syndrome within a few days after onset of measles infection are reported from the University of Catania, Italy. The cases occurred during measles epidemics in Italy (1988 and 1992) and the UK (1988). Spontaneous burning pain, increased by stimulation, or loss of pain sensation, over one side of the body was associated with mild ipsilateral paralysis. MRI showed bilateral swelling of thalamic areas and deep cerebral vein thrombosis. Symptoms remitted and MRI abnormalities resolved over a period of weeks or months. [1]

COMMENT. Acute measles infection may be complicated by deep cerebral venous thrombosis and symptoms of the thalamic syndrome. The symptoms can resolve without serious sequelae.