The clinical manifestations and genetic aspects in 147 children with benign focal sharp waves were evaluated at the Epilepsy Center, Raisdorf, Germany. Seizures in 134 patients included febrile convulsions (26%), rolandic seizures (24%), neonatal (6%), generalized tonic-clonic (49%), and rare complex partial. Transmission of FC showed a maternal preponderance. The phenotypic expression of the genetic basis for focal sharp waves was remarkably variable. The clinical and EEG findings suggested a multifactorial pathogenesis for epilepsies characterized by benign focal sharp waves. 
COMMENT. Focal sharp waves may be characteristic of a variety of different seizure patterns, including febrile convulsions, and not only that of rolandic epilepsy. In addition to epileptic syndromes, focal sharp waves may be found in children with learning disabilities such as dyslexia and dysphasia. The genetics of these syndromes appears to be multifactorial.
Genetics of febrile convulsions. Doose H and Maurer A have also reported on genetic factors in febrile convulsions . The risk was 10%; only FC in 64% of affected offspring. Offspring of females with affected parents were at increased risk.