A case of radiation-induced meningioma that appeared in a 27-year-old woman, 12 years after treatment of a childhood-onset posterior fossa medulloblastoma, is reported from the Department of Neurosurgery, Bretonneau Hospital, Tours, France. She was admitted with a left facial neuralgia and transitory aphasia. MRI showed a large left temporal mass which was removed surgically. Histopathological examination was consistent with a meningotheliomatous meningioma. Eight months later the patient was readmitted with ataxia, memory disturbances, and left lower limb paresis. CT showed multiple intracerebral tumors in the left temporal area, posterior fossa, and interhemisperic area. Removal of the largest tumor showed a medulloblastoma recurrence. Despite chemotherapy, the patient deteriorated and died. [1]

COMMENT. Glial and meningeal cells are most commonly involved in radiation-induced neoplasms. Meningiomas may occur after low-dose, intermediate, or high-dose irradiation of the head. The meninges of children are particularly susceptible. The majority of radiation-induced meningiomas are situated in the falx and parasagittal area or over the convexity of the skull. The temporal and sphenoidal location of the above reported meningioma folowing irradiation is unusual.